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SlashTCO.com: Linux Cluster Powers Baylor College of Medicine Supercomputer

Mar 15, 2001, 14:29 (0 Talkback[s])

[ Thanks to Russ Foster for this link. ]

"Understanding the structural makeup and functions of microscopic proteins is one focus of research currently underway at the National Center for Macromolecular Imaging (NCMI) at Baylor College of Medicine in Houston, Texas."

"The research involves creating 3-D images of microscopic proteins, which scientists then observe from all directions to determine how an individual protein functions. Reconstructing these 3-D models is accomplished through a process called single particle reconstruction, an extremely compute intensive operation."

"Protein molecules are responsible for performing most of the active functions within cells," said Steven Ludtke, computational biologist for NCMI. "For example, proteins called ion-channels serve as switches, which control chemical flow into and out of a cell. These switches are 10 to 1,000 times smaller than a single transistor in an integrated circuit."

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