"What would you get if you were to combine good graphic programs such as the GNU Image Manipulation Program (GIMP), Inkscape, and CinePaint with other open source biggies such as Scribus and Nvu? The answer: Grafpup Linux, a live CD heaven for all graphic designers.
"Based on Puppy Linux, Grafpup is a small distribution despite its plethora of tools. Download the 75MB ISO and you'll be amazed at its speed and simplicity. When running from the live CD, Grafpup loads the entire operating system into your RAM, ensuring that the applications run instantly. The first time you run the live CD, Grafpup saves a file called 'pup101' on your hard disk that contains settings for your keyboard layout, mouse type, and more, so that you don't need to configure your machine each time you boot. Every successive boot completes in less than 20 seconds..."
