"We have examined several applications for working with Flickr before, and they all have one thing in common: they focus on uploading images from the desktop. But uploading only scratches the surface of what the Web service can do. Desktop Flickr Organizer (DFO) gives you a lot more power.
"There is nothing wrong with Flickr uploaders, but if you are a heavy Flickr user, you need to do more than just upload pictures..."