"Of course, from an IT perspective, the most serious shortcoming
of Web-based applications is their perceived lack of security. In
particular, Google doesn't let you encrypt the data you store on
the company's servers. Zoho's FAQ page states that the company will
soon add a data-encryption option. Still, storing the
organization's data on somebody else's servers can give system
administrators nightmares.
"There are still some applications I use regularly that don't
have a Web equivalent: Outlook, the TopStyle HTML editor, and the
Corel Paint Shop Pro imaging program, among a handful of others.
The one thing all three of these programs have in common is that
they were selected for me--by my boss."