"There was some software I had to change when I made the switch,
but I was planning to do so anyway. For data analysis instead of
SPSS, I learned R, which is more powerful (see these notes for
getting R and a GUI interface installed on Ubuntu). I had to find a
different tool to make screencasts. Luckily they are all free in
Linux. I used gtk-recordmydesktop, but there are also Istanbul,
WebcamStudio, and others. For music instead of Winamp there was the
winamp-clone xmms (and now Audacious). Of course there are itunes
alternatives too."