Using LiLi to create a Bootable, Portable and Virtualized USB Drive

“Typically, Linux USB drives require rebooting to install
software. It is possible to create a Linux USB drive that will
install without a reboot. This is where LiLi comes into play.

By setting drive persistence for the USB, you are able to save
files and settings on the USB which would normally be lost once the
Linux USB drive is dismounted.

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