When you create a regular Linux live USB, you can install software, download files, make changes to the system, and so on, but all of these changes are lost after a reboot. A persistent live USB allows saving any changes you make to the live system, so the they are still present the next time you boot to it. This article explains creating a persistent live USB with Ubuntu (and flavors like Kubuntu, Xubuntu, Ubuntu MATE, etc.), Linux Mint, Debian or elementary OS (it should work with any Debian or Ubuntu based Linux distribution), using mkusb.
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