Point Linux 2.2 is a Debian based distro that utilises the Mate desktop. It looks a lot like Ubuntu did before Unity came along and performs incredibly well.
A request came in a few weeks ago to review the Point Linux operating system. I had already downloaded Point Linux with a view to reviewing it anyway so I bumped it up the queue a bit.
According to the Point Linux WIKI page, Point Linux is a desktop distro aimed towards experienced users and the business/IT sector.